Use the search bar to search by drug, manufacturer, or indication. You can also filter your search results by drug, manufacturer, or negotiation status.
To learn more about a specific file, click on a drug name. It will open its product card, which includes information about the manufacturer, indication (the approved use of a drug by Health Canada), and negotiation milestones.
There are 6 negotiation statuses, which reflect where the drug file is in the pCPA process:
Under consideration for negotiation
We’re considering the evidence and gathering other information to inform the negotiation approach, including eligibility for expedited negotiation pathways.
Active negotiation
Negotiation activities are underway for the drug, with our negotiation team and the manufacturer meeting regularly.
Concluded with an LOI
Negotiations ended successfully with mutually agreed-upon terms, and these terms are outlined in a letter of intent (LOI).
Concluded without agreement
Negotiating parties couldn’t agree on terms. Negotiations have ended without a pricing agreement for the drug.
Negotiation not pursued
It has been decided, in partnership with our member drug plans, not to engage in a negotiation. Typically, this is because the drug’s health technology (HTA) assessment reimbursement recommendations were negative, or “do not reimburse.” Other reasons, like the manufacturer declining to negotiate or a lack of supply of the drug in Canada, may be reflected in an accompanying status note.
Negotiation on hold
We began negotiation activities for the drug, but they’ve since been paused. An accompanying status note indicates whether the pause was requested by the manufacturer or the pCPA.
Learn more
To learn more about our negotiation processes, or where the pCPA fits into the Canadian drug reimbursement system, consult these pages:
Status:
Active negotiation
Manufacturer:
Astellas Pharma Inc.
Indication:
For post-transplant maintenance for measurable residual disease (MRD) positive FLT3-ITD mutated acute myeloid leukemia (AML).
Last updated:
September 9, 2026
Status:
Active negotiation
Manufacturer:
Hill Dermaceuticals, Inc.
Indication:
Actinic keratosis
Last updated:
September 9, 2026
Status:
Under consideration for negotiation
Manufacturer:
Eli Lilly Canada Inc.
Indication:
For once-weekly administration for chronic weight management, including weight loss and weight maintenance, as an adjunct to a reduced-calorie diet and increased physical activity, in adults with an initial body mass index of: 30 kg/m2 or greater (obesity), or 27 kg/m2 to less than 30 kg/m2 (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, dyslipidemia, prediabetes, type 2 diabetes mellitus, obstructive sleep apnea, or cardiovascular disease).
Last updated:
September 3, 2026
Status:
Active negotiation
Manufacturer:
Sanofi-Aventis Canada Inc.
Indication:
For the treatment of adults with acquired thrombotic thrombocytopenic purpura in combination with plasma exchange and immunosuppressive therapy
Last updated:
September 3, 2026
Status:
Under consideration for negotiation
Manufacturer:
Novartis Pharmaceuticals Canada Inc.
Indication:
For the treatment of adult patients with C3 glomerulopathy (C3G) to reduce proteinuria
Last updated:
July 13, 2026
Status:
Active negotiation
Manufacturer:
Sobi Canada Inc.
Indication:
For the treatment of adult and pediatric patients aged 12 years and older with C3 glomerulopathy or primary immune-complex membranoproliferative lomerulonephritis to reduce proteinuria.
Last updated:
September 3, 2026
Status:
Under consideration for negotiation
Manufacturer:
Eisai Limited
Indication:
for the treatment of patients with a clinical diagnosis of mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease (early Alzheimer's disease) who are apolipoprotein E ε4 (ApoE4) noncarriers or heterozygotes, and who have confirmed amyloid pathology.
Last updated:
September 3, 2026
Yorvipath (palopegteriparatide)
Status:
Under consideration for negotiation
Manufacturer:
Pendopharm, a division of Pharmascience Inc.
Indication:
A parathyroid hormone (PTH) replacement therapy indicated for the treatment of chronic hypoparathyroidism in adults
Last updated:
September 3, 2026
Welireg (Active ENP) (belzutifan)
Status:
Active negotiation
Manufacturer:
Merck Canada Inc.
Indication:
for treatment of adult and pediatric (12 years and older) patients with locally advanced, unresectable, or metastatic pheochromocytoma or paraganglioma (PPGL)
Last updated:
September 2, 2026
Status:
Active negotiation
Manufacturer:
Arcutis Biotherapeutics, Inc.
Indication:
For the topical treatment of plaque psoriasis of the scalp and body in
Last updated:
September 2, 2026