Use the search bar to search by drug, manufacturer, or indication. You can also filter your search results by drug, manufacturer, or negotiation status.
To learn more about a specific file, click on a drug name. It will open its product card, which includes information about the manufacturer, indication (the approved use of a drug by Health Canada), and negotiation milestones.
There are 6 negotiation statuses, which reflect where the drug file is in the pCPA process:
Under consideration for negotiation
We’re considering the evidence and gathering other information to inform the negotiation approach, including eligibility for expedited negotiation pathways.
Active negotiation
Negotiation activities are underway for the drug, with our negotiation team and the manufacturer meeting regularly.
Concluded with an LOI
Negotiations ended successfully with mutually agreed-upon terms, and these terms are outlined in a letter of intent (LOI).
Concluded without agreement
Negotiating parties couldn’t agree on terms. Negotiations have ended without a pricing agreement for the drug.
Negotiation not pursued
It has been decided, in partnership with our member drug plans, not to engage in a negotiation. Typically, this is because the drug’s health technology (HTA) assessment reimbursement recommendations were negative, or “do not reimburse.” Other reasons, like the manufacturer declining to negotiate or a lack of supply of the drug in Canada, may be reflected in an accompanying status note.
Negotiation on hold
We began negotiation activities for the drug, but they’ve since been paused. An accompanying status note indicates whether the pause was requested by the manufacturer or the pCPA.
Learn more
To learn more about our negotiation processes, or where the pCPA fits into the Canadian drug reimbursement system, consult these pages:
Status:
Under consideration for negotiation
Manufacturer:
HLS Therapeutics Inc.
Indication:
Primary hyperlipidemia and cardiovascular disease
Last updated:
August 11, 2026
Status:
Under consideration for negotiation
Manufacturer:
Pfizer Canada ULC
Indication:
For the treatment of adults and adolescents 12 years and older with severe alopecia areata
Last updated:
August 11, 2026
Status:
Concluded with an LOI
Manufacturer:
Hoffmann-La Roche Ltd.
Indication:
In combination with trastuzumab and chemotherapy for the neoadjuvant treatment of adult patients with early-stage HER2-positive breast cancer
Last updated:
August 11, 2026
Status:
Under consideration for negotiation
Manufacturer:
Arrowhead Pharmaceuticals
Indication:
As an adjunct to diet to reduce triglyceride levels for adult patients with genetically confirmed or clinically diagnosed familial chylomicronemia syndrome (FCS) for whom standard triglyceride lowering therapies have been inadequate.
Last updated:
August 10, 2026
Status:
Under consideration for negotiation
Manufacturer:
AbbVie Corporation
Indication:
For the acute treatment of migraine, with or without aura, in adults
Last updated:
August 10, 2026
Status:
Concluded with an LOI
Manufacturer:
LEO Pharma Inc.
Indication:
Chronic hand eczema
Last updated:
August 4, 2026
Status:
Concluded without agreement
Manufacturer:
Eli Lilly Canada Inc.
Indication:
Braftovi, in combination with cetuximab and mFOLFOX6, for the treatment of patients with metastatic colorectal cancer (mCRC) with a BRAF V600E mutation, as detected by a validated test
Last updated:
July 31, 2026
Status:
Active negotiation
Manufacturer:
Pfizer Canada ULC
Indication:
For the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least three prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody, and have demonstrated disease progression on or after the last therapy.
Last updated:
July 31, 2026
Talvey (Active ENP) (talquetamab)
Status:
Active negotiation
Manufacturer:
Janssen Inc.
Indication:
for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least three prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody, and have demonstrated disease progression on or after the last therapy
Last updated:
July 28, 2026
Status:
Under consideration for negotiation
Manufacturer:
Hoffmann-La Roche Ltd.
Indication:
As monotherapy for the treatment of adult patients with relapsed or refractory follicular lymphoma (Grades 1 – 3a) who have received at least two prior lines of systemic therapy.
Last updated:
July 28, 2026