Use the search bar to search by drug, manufacturer, or indication. You can also filter your search results by drug, manufacturer, or negotiation status.
To learn more about a specific file, click on a drug name. It will open its product card, which includes information about the manufacturer, indication (the approved use of a drug by Health Canada), and negotiation milestones.
There are 6 negotiation statuses, which reflect where the drug file is in the pCPA process:
Under consideration for negotiation
We’re considering the evidence and gathering other information to inform the negotiation approach, including eligibility for expedited negotiation pathways.
Active negotiation
Negotiation activities are underway for the drug, with our negotiation team and the manufacturer meeting regularly.
Concluded with an LOI
Negotiations ended successfully with mutually agreed-upon terms, and these terms are outlined in a letter of intent (LOI).
Concluded without agreement
Negotiating parties couldn’t agree on terms. Negotiations have ended without a pricing agreement for the drug.
Negotiation not pursued
It has been decided, in partnership with our member drug plans, not to engage in a negotiation. Typically, this is because the drug’s health technology (HTA) assessment reimbursement recommendations were negative, or “do not reimburse.” Other reasons, like the manufacturer declining to negotiate or a lack of supply of the drug in Canada, may be reflected in an accompanying status note.
Negotiation on hold
We began negotiation activities for the drug, but they’ve since been paused. An accompanying status note indicates whether the pause was requested by the manufacturer or the pCPA.
Learn more
To learn more about our negotiation processes, or where the pCPA fits into the Canadian drug reimbursement system, consult these pages:
Status:
Concluded with an LOI
Manufacturer:
Hoffmann-La Roche Ltd.
Indication:
In combination with palbociclib and fulvestrant for the treatment of adult patients with endocrine resistant, PIK3CA-mutated, hormone receptor-positive (HR+) (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, following recurrence on or after completing adjuvant endocrine treatment.
Last updated:
May 26, 2026
Status:
Active negotiation
Manufacturer:
Hoffmann-La Roche Ltd.
Indication:
For the first-line treatment of patients with metastatic NSCLC whose tumours have high PD-L1 expression (PD-L1 stained greater than or equal to 50% of TCs or PD-L1 stained tumour-infiltrating immune cells [ICs] covering greater than or equal to 10% of the tumour area), as determined by a validated test and who do not have EGFR or ALK genomic tumour aberrations.
Last updated:
May 25, 2026
Status:
Concluded with an LOI
Manufacturer:
Bausch Health, Canada Inc.
Indication:
Schizophrenia in Adults
Last updated:
May 25, 2026
Quillivant ER (Methylphenidate Hydrochloride)
Status:
Active negotiation
Manufacturer:
KYE Pharmaceuticals Inc.
Indication:
Attention-deficit/hyperactivity disorder (ADHD)
Last updated:
May 21, 2026
Status:
Under consideration for negotiation
Manufacturer:
Hill Dermaceuticals, Inc.
Indication:
Actinic keratosis
Last updated:
May 20, 2026
Status:
Under consideration for negotiation
Manufacturer:
Hill Dermaceuticals, Inc.
Indication:
Actinic keratosis
Last updated:
May 20, 2026
Status:
Concluded with an LOI
Manufacturer:
Novartis Pharmaceuticals Canada Inc.
Indication:
Adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase
Last updated:
May 20, 2026
Status:
Concluded without agreement
Manufacturer:
Incyte Biosciences Canada Corporation
Indication:
Atopic dermatitis
Last updated:
May 20, 2026
Elahere (mirvetuximab soravtansine)
Status:
Concluded without agreement
Manufacturer:
AbbVie Corporation
Indication:
For the treatment of adult patients with folate receptor-alpha (FRα) positive*, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, who have received one to three prior systemic treatment regimens.
Last updated:
May 14, 2026
Status:
Under consideration for negotiation
Manufacturer:
Merck Canada Inc.
Indication:
for treatment of adult and pediatric (12 years and older) patients with locally advanced, unresectable, or metastatic pheochromocytoma or paraganglioma (PPGL)
Last updated:
May 8, 2026