Use the search bar to search by drug, manufacturer, or indication. You can also filter your search results by drug, manufacturer, or negotiation status.
To learn more about a specific file, click on a drug name. It will open its product card, which includes information about the manufacturer, indication (the approved use of a drug by Health Canada), and negotiation milestones.
There are 6 negotiation statuses, which reflect where the drug file is in the pCPA process:
Under consideration for negotiation
We’re considering the evidence and gathering other information to inform the negotiation approach, including eligibility for expedited negotiation pathways.
Active negotiation
Negotiation activities are underway for the drug, with our negotiation team and the manufacturer meeting regularly.
Concluded with an LOI
Negotiations ended successfully with mutually agreed-upon terms, and these terms are outlined in a letter of intent (LOI).
Concluded without agreement
Negotiating parties couldn’t agree on terms. Negotiations have ended without a pricing agreement for the drug.
Negotiation not pursued
It has been decided, in partnership with our member drug plans, not to engage in a negotiation. Typically, this is because the drug’s health technology (HTA) assessment reimbursement recommendations were negative, or “do not reimburse.” Other reasons, like the manufacturer declining to negotiate or a lack of supply of the drug in Canada, may be reflected in an accompanying status note.
Negotiation on hold
We began negotiation activities for the drug, but they’ve since been paused. An accompanying status note indicates whether the pause was requested by the manufacturer or the pCPA.
Learn more
To learn more about our negotiation processes, or where the pCPA fits into the Canadian drug reimbursement system, consult these pages:
Status:
Concluded with an LOI
Manufacturer:
AbbVie Corporation
Indication:
Rheumatoid Arthritis
Last updated:
August 8, 2022
pdp-levETIRAcetam (levetiracetam)
Status:
Concluded with an LOI
Manufacturer:
Pendopharm, a division of Pharmascience Inc.
Indication:
Epilepsy
Last updated:
August 5, 2022
Status:
Negotiations were not pursued
Manufacturer:
Incyte Biosciences Canada Corporation
Indication:
Unresectable Locally Advanced or Metastatic Cholangiocarcinoma (CCA) in adults with previously treated CCA with a FGFR2 fusion or other rearrangement
Last updated:
July 29, 2022
Status:
Concluded without agreement
Manufacturer:
AVIR Pharma Inc.
Indication:
Eosinophilic Esophagitis (Maintenance)
Last updated:
July 20, 2022
Status:
Concluded without agreement
Manufacturer:
AVIR Pharma Inc.
Indication:
Eosinophilic Esophagitis (Induction)
Last updated:
July 20, 2022
Trikafta (elexacaftor/tezacaftor/ivacaftor and ivacaftor)
Status:
Concluded with an LOI
Manufacturer:
Vertex Pharmaceuticals (Canada) Incorporated
Indication:
Cystic Fibrosis, F508del CFTR mutation in patients aged 6 years and older
Last updated:
July 7, 2022
Status:
Concluded with an LOI
Manufacturer:
Pfizer Canada ULC
Indication:
Metastatic colorectal cancer (mCRC) in patients with a BRAF V600E mutation, as detected by a validated test, after prior therapy (in combination with cetuximab)
Last updated:
July 6, 2022
Braftovi/Mektovi (encorfenib/binimetinib)
Status:
Concluded with an LOI
Manufacturer:
Pfizer Canada ULC
Indication:
Unresectable or metastatic melanoma with a BRAF V600 mutation, as detected by a validated test, (encorafenib and binimetinib in combination)
Last updated:
July 6, 2022
Status:
Concluded without agreement
Manufacturer:
Sanofi Genzyme Canada
Indication:
Asthma
Last updated:
June 28, 2022
Status:
Concluded with an LOI
Manufacturer:
Hoffmann-La Roche Ltd.
Indication:
Neuromyelitis optica spectrum disorder (NMOSD)
Last updated:
June 28, 2022